Abstract Library

#2264 Metastatic Insulinoma: A Case-report of Complete Response to Peptide Receptor Radionuclide Therapy

Introduction: Insulinoma is a rare pancreatic neuroendocrine tumour. Metastatic insulinomas are a major therapeutic challenge.

Conference: 15th Annual ENETSConcerence (2018)

Presenting Author:

Authors: Martins Branco D, Lucena Sampaio I, Brito M, Claro I,

Keywords: Insulinoma, PRRNT,

#1870 Detection of Metastatic Insulinoma with 68Ga-NODAGA-Exendin-4 PET/CT in a Young Child – A Case Report

Introduction: Malignant insulinomas are extremely rare in children. Localizing metastases of insulinoma is challenging. Imaging modalities like CT and MRI show limited results. Somatostatin-receptor (SSTR) imaging (SRS) performs better. However, a subgroup of malignant insulinoma lack SSRT-2 and can, therefore, not be localized using SRS. We propose that in these cases GLP-1R imaging, using the stable GLP-1 analog exendin, could play an important role.

Conference: 14th Annual ENETSConcerence (2017)

Presenting Author: Boss M

Authors: Boss M, de Herder W, Hussain K, Shah P, Brom M,

Keywords: Metastatic insulinoma, GLP-1R, PET, exendin,

#502 Bifunctional ShRNAimPDX-1 Therapy Prevents Hypoglycemic Death From Insulinoma in Mice

Introduction: PDX-1 is a novel molecular target for insulinoma. Bi-functional shRNAi platform has been developed that results in a more effective targeted gene knockdown.

Conference: 9th Annual ENETSConcerence (2012)

Presenting Author:

Authors: Liu S, Wang Z, Shahi K, Rao D, Zhou G,

Keywords: PDX-1, bi-shRNAi, insulinoma, target,

#483 Efficacy of Everolimus in Patients with Metastatic Insulinomas and Refractory Hypoglycemia: For the French Group of Endocrine Tumors (GTE-Renaten)

Introduction: Refractory hypoglycemia in patients with metastatic insulinomas (RHMI) is an important cause of morbidity and mortality and Everolimus could be a new therapeutic option.

Conference: 9th Annual ENETSConcerence (2012)

Presenting Author:

Authors: Bernard V, Lombard-Bohas C, Goichot B, Rohmer V, Guimbaud R,

Keywords: pancreatic endocrine tumor, insulinoma, Everolimus, hypoglycemia,

#425 Successful Treatment with Everolimus of Functioning Liver Metastases From a Pancreatic Insulinoma

Introduction: Medical treatment of metastatic insulinoma is debated.

Conference: 9th Annual ENETSConcerence (2012)

Presenting Author:

Authors: Zatelli M, Ambrosio M, Franceschetti P, Lunardon S, Bondanelli M,

Keywords: Everolimus, insulinoma,